The Essential Oil Composition and Antioxidant Activity of Achillea spp. Growing in the Southwest of Iran

Authors

1 Department of Agronomy and Plant Breeding, Shoushtar Branch, Islamic Azad University, Shoushtar, Iran

2 Department of Food Industry, Shoushtar Branch, Islamic Azad University, Shoushtar, Iran

Abstract

The composition of essential oil isolated from Achillea eriophora, Achillea millefolium, Achillea biebersteinii and Achillea tenuifolia growing wild in the south west of Iran, was analyzed.  A. eriophora, A. millefolium and A. tenuifolia essential oils were characterized by sabinene, 1, 8-cineole, terpinene-4-ol, ά –bisabolol, p-Cymene, β-pinene and α-pinene. The A. biebersteinii essential oil was characterized by sabinene, borneol, camphor, piperitone and α-pinene. Antioxidant activity was analyzed using the 1,1-diphenyl-2- picrylhydrazyl free radical scavenging  and Fe 3+ reducing power methods. Results indicated essential oil obtained from A. eriophora, A. millefolium, A. tenuifolia and A. biebersteinii exhibited a dose-dependent increase with a radical scavenging effect of 85.0%, 82.0% , 82.0% and 64.0% at 350 μg/ml, which are close to the 1,1-diphenyl-2- picrylhydrazyl inhibition of the positive control Butylated Hydroxytoluene (88.0%) at the same concentration. It was shown that the A. biebersteinii essential oil exhibited the weakest antioxidant effect than Butylated Hydroxytoluene or other Achillea spp. essential oils. In this study chamazulene, ά-bisabolol and ά –bisabolol oxide percentage were higher in A. eriophora, A. millefolium and A. tenuifolia essential oil compared to A. biebersteinii essential oil and  these compounds improved antioxidant capacity of  Achillea spp.

Keywords

References

1. Bua-In S, Paisooksantivatana Y.  Essential Oil and Antioxidant Activity of Cassumunar Ginger (Zingiberaceae: Zingibermontanum) Collected from Various Parts of Thailand.  Kasetsart J. 2009;43:467- 475.
2. Jaimand K, Rezaee MB, Comparative study of the essential oils of three Achillea species from Iran. J Essent Oil Res. 2001;13:354-356.
3. McKay DL, Blumberg JB. A review of the bioactivity and potential health benefits of chamomile tea (Matricaria recutita L.). Phytother Res. 2006;20:519-530.
4. Rechinger KH. Flora Iranica. No. 158. AkademischeDruke-U. Verlagsanstalt, Wien, Austria. 1963;49-71.
5. Asgarirad  H, Pourmorad F , Hosseinimehr S J, Saeidnia S,  Ebrahimzadeh M A,  Lotfi F. In vitro antioxidant analysis of Achillea tenuifolia. Afr J  Biotechnol. 2010;9:3536-354.
6. Gharibi S, Rahimmalek M, Mirlohi A,  Majidi M M, SayedTabatabaei B E. Assessment of genetic diversity in Achillea millefolium subsp. millefolium and Achillea millefolium subsp. elbursensis using morphological and ISSR markers. J Med Plant Res. 2011;5:2413-2423.
7. Rustaiyan A, Komeilizadeh H, Shariatpanahi M S.  Comparative study of the essential oils of three Achillea Species from Iran. J Essent Oil Res. 1998;10:207-209.
8. Smelcorevic A,   Lamshoeft M, Radulovic N, Ilic D, Palic R.  LC/MS analysis of the essential oils of Achillea millefolium and Achillea  crithmifolia. 2010;71:113-116.
9. Perry RJ, Watson P, Hodges JR. The nature and staging of attention dysfunction in early (minimal and mil) Alzheimer‘s disease: relationship to episodic and semantic memory impairment. Neuropsychology. 2000;38:252-271.
10. Gulcin I, Buyukokuroglu ME, Oktay M, Kufrevioglu O I.On the in vitro antioxidative properties of melatonin. J Pineal Res. 2002;33:167-171.
11. Shahidi F. Antioxidants in food and food antioxidants. Nahrung, 2000;44:158-163.
12. Burk RD, ZbigniewCichacz A, Daskalova S M. Aqueous extract of Achillea millefolium L. (Asteraceae) inflorescences suppresses lipopolysaccharide-induced inflammatory responses in RAW 264.7 murine Macrophages. J Med Plant Res. 2010;4:225-234.
13. Candan F, Unlu M, Tepe B, Daferera D, Polissiou M, Sökmen A, Akpulat H A. Antioxidant and antimicrobial activity of the essential oil and methanol extracts of Achillea millefolium subsp. Millefolium Afan. (Asteraceae). J Ethnopharmacol. 2003;87:215-220.
14. Hernández-Ceruelos A, Madrigal-Santillán E, Morales-González JA, Chamorro-Cevallos G,  Cassani-Galindo M, Madrigal-Bujaidar E.  Antigenotoxic effect of Chamomilla recutita essential oil in mouse spermatogonial cells, and determination of its antioxidant capacity in vitro. Int J Mol Sci. 2010;11:3793-3802.
15. British Pharmacopoeia commission. British Approved Names. A dictionary of Drug Names for Regulatory use in the UK, second ed. The Stationary Office Publisher, London.2002.
16. Adams RP.  Identification of essential oil components by gas chromatography /quadrupole mass spectroscopy.  Allured Publishing Corporation, Carol Stream, Illinois., 2001.
17. Jaimand K, Rezaee MB, Comparative study of the essential oils of three Achillea species from Iran. J Essent Oil Res. 2001;13:354-356.
18. Yildirim A, Mavi A, Oktay M, Kara A, Algur Ö F, Bilaloglu V. Comparison of antioxidant and antimicrobial activities of Tilia (Tiliaargentea), sage (Salvia triloba L.) and black tea (Camellia sinensis) extracts. J Agric Food Chem. 2001;48:5030-5034.
19. Baghalian K, Abdoshah S, Khalighi-Sigaroodi F, Paknejad F. Physiological and phytochemical response to drought stress of German chamomile (Matricaria recutita L.). Plant Physiol Biochem, 2011;49:201-207.
20. Benedek B, Rothwangl-Wiltschnigg  K, Rozema E, Gjoncaj N,  Reznicek G J, Jurenitsch, B., Kopp, S., Glasl, A. Yarrow (Achillea millefolium L.): pharmaceutical quality of commercial samples. Pharmazie. 2008;63:23-26.
21. Nadim MM, Malik AA, Ahmad J, Bakshi SK. The essential oil composition of Achillea millefolium L. cultivated under tropical condition in India. World J Agric Sci. 2001;7:561-565.
22. Ho JC.  Chemical composition and bioactivity of essential oil of seed and leaf from Alpiniaspeciosa grown in Taiwan. J Chinese Chem Soc. 2010;57:758-757.
23. Kadri A, Zarai Z, Ben Chobba I, Békir A, N. Gharsallah M,  Damak R, Gdoura R. Chemical constituents and antioxidant properties of Rosmarinus officinalis L. essential oil cultivated from South-Western Tunisia, J Med Plant Res. 2010;5:5999-6004.
24. Baghalian K, Haghiry A, Naghavi M R, Mohammadi A. Effect of saline irrigation water on agronomical and phytochemical characters of chamomile (Matricaria recutita L.). Scientia Horticulturae, 2008;116:437-441.
25. Houghton PJ.   Activity and constituents of Sage relevant to the potential treatment of symptoms of Alzheimer’s disease. Herbal Gram, 2004;61:38-54.
26. Baris Z, Medine GLL, FikrettinSahun CE, Zer  H, Kili H,  Zkan H,  Kment MS,  Ozbek T. Biological activities of the essential oil and methanol extract of Achillea biebersteinii  (Asteraceae). Turk J Biol. 2003;30:65-73.
27. Konyalioglu S, Karamenderes C. The protective effects of Achillea L. species native in Turkey against H2O2-induced oxidative damage in human erythrocytes and leucocytes. J Ethnopharmacol. 2005;102:221-227.
28. Rezaeipoor R, Saeidnia S, Kamalinejad M. Immuno-suppressive Activity of Achillea talagonica on humoral immune responses in experimental animals. J. Ethnopharmacol. 1999;65:273-276.
29. Rekka EA, Kourounakis AP, Kourounakis P N. Investigation on the effect of chamazulene on lipid peroxidation and free radical processes. Res. Commun. Mol. Pathol. Pharmacol.1996;92:361-364.
30. Lis-Balchin M, Deans G, Eaglesham E. Relationship between bioactivity and chemical composition of commercial essential oils. Flavour Fragr J. 1998;13:98-104.
Journal of Medicinal plants and By-Products
Volume 2, Issue 2
September 2013
Pages 123-130

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