Antioxidant Activity and Chemical Composition of the Essential oil of Ducrosia anethifolia (DC.) Boiss. from Neyriz

Authors

1 Department of Chemistry, Faculty of Science, University of Sistan & Baluchestan, Zahedan, Iran

2 Medicinal and Ornamental Plants Research Institute, University of Sistan & Baluchestan, Zahedan, Iran

Abstract

Ducrosia anethifolia (DC.) Boiss. is belongs to the Apiaceae family. It is one of the three species of Iranian Ducrosia Boiss. species growing wild in several areas of the country. In this research, we extracted the essential oil and it analyzed by GC/MS. The analysis of essential oil from leaves of D. anethifolia about 19 constituents was identifed and percentage composition was determined (94.9%). The major constituents identified by this method were α-pinene (70.3%), β-myrcene (6.9%), β-pinene (6.3%), limonene (4.9%). So, extracts of this species extracted by maceration method and antioxidant activity evaluated by 1,1-diphenyl-2-picrylhydrazyl (DPPH). Results showed that antioxidant activity of D. anethifolia in ethanolic and ethyl acetate extracts are less than Butylated hydroxytoluene (BHT) as a synthetic antioxidant which used for positive control. Although, antioxidant activity of ethanolic extract is more than ethyl acetate extract, but inhibitory power of this extracts is low.

Keywords


1. Aynehchi Y. Materia Medica and Iranian medicinal plants, Tehran University Publications, 1991.

2. Mozaffarian V. A dictionary of Iranian plant names, Tehran, Farhang Moaser, 1996.

3. Haghi G, Safaei A, Safari J. Extraction and determination of the main components of the essential oil of Ducrosia anethifolia by GC and GC/MS. Iranian J Pharm Res. 2004;3(Suppl. 2):275.

4. Al‐Meshal IA. Isolation and characterization of a bioactive volatile oil from Ducrosia ismaelis Asch Res. Commun Chem Pathol Pharmacol., 1986; 54129-54132.

5. Stavri M, Mathew KT, Bucar F, Gibbons S. Pangelin, an antimycobacterial coumarin from Ducrosia anethifolia Planta Med.. 2003;69956-69959.

6. Sefidkon F and Javidtash I,. Essential oil composition of Ducrosia anethifolia (DC.) Boiss. from Iran. J. Essential Oil. 2002;14278-14279.

7. Al‐Meshal IA, Khalifa TI, Hassan MMA. Physico‐chemical characteristics and spectroscopy of Ducrosia ismaelis oil. Spectroscopy Letters. 1985;18:491-496.

8. Rustaiyan A, Mazloomifar H, Masoudi SH, Aghjani Z. Volatile oil of Ducrosia assadii Alava. and Prangos acaulis (DC.) Bornm. from Iran. J Essential Oil. 2006;18,682-684.

9. Shahabipour S, Firuzi O, Asadollahi M, Faghihmirzaei E, Javidnia K. Essential oil composition and cytotoxic activity of Ducrosia anethifolia and D.flabellifolia from Iran. J. Essential Oil Research. 2013;25:160-163.

10. Janssen AM, Scheffer, JJC, Baerheim Svendsen A, Aynehchi Y. The essential oil of Ducrosia anethifolia (DC.) Boiss Chemical composition and antimicrobial activity. Pharm Weekbl Sci.. 1984;6:157-160.

11. Mostafavi A, Afzali D, Mirtadzadini S. Chemical composition of the essential oil of Ducrosia anethifolia (DC.) Boiss. from Kerman Province in Iran. J. Essential Oil Research. 2008;20:509-512.

12. Hajhashemi V, Rabbani M, Ghanadi A, Davari E. Evaluation of antianxiety and sedative effects of essential oil of Ducrosia anethifolia in mice. Clinics. 2010;65:1037-1042.

13. Mostafavi A, Shamspur T, Afzali D, Mirtadzadini S. Chemical composition of the essential oil of Ducrosia assadii Alava. from Kerman Province in Iran. J Essential Oil Research. 2010;22:300-302.

14. Assadipour A, Sharififar F, Robati M, Samzadeh V, Esmaeilpour Kh. Composition and Antioxidant Effect of the Essential Oils of the Flowers and Fruits of Ducrosia assadii Alava. a Unique Endemic Plant from Iran. J Biologi Sci.. 2013;13:288-292.

15. Brand-Williams W, Cuvelier ME, Berset C. Use of a free radical method to evaluate antioxidant activity, LWT-Food Science and Technology, 1995:25-30.