Ethnobotanical and Phytochemical Study of Withania coagulans (Stocks) Dunal in Khash City, Iran

Document Type : Research Paper

Authors

Department of Range and Watershed Management, University of Zabol, Zabol, Iran

Abstract

Indigenous knowledge of medicinal plants covers various aspects, including ethnobotany. Ethnobotany means human knowledge of botany and the ecology of plants. In this study, an ethnobotanical and phytochemical evaluation of Withania coagulans (Stocks) Dunal was performed in Khash city in Sistan and Baluchestan province. The data collection was performed through a structured questionnaire (150 questionnaires). The data was analyzed using RFC (Relative Frequency of Citation) and CI (Cultural Importance Index). The questions were related to the plant organ used, plant harvest time, type of livestock user and growth place. To investigate which chemical compounds in the plant cause people to use this drug in the treatment of certain diseases, the chemical compounds of the species were analyzed by GC and GC/MS. Results showed that the best season of plant collecting was spring. The most used part of the plant was seeds. The plant grows mainly in plains. Camel (51.40%) and sheep (42.05%) have the maximum use of the plant. The maximum chemical compositions were related to the Ar-tumerone terpene and Pentadecanone with 95.5% and 93.8% probability, respectively. Also, the percentage of saturated fatty acids such as Palmitic acid, Tetradecanoic acid and unsaturated fatty acids such as Oleic acid has the highest percentage. In total, indigenous people use this plant in treating diabetes due to the presence of a compound such as Ar-tumerone, which is consistent with the chemical compounds identified in this study. The importance of plant seeds in cheese making by indigenous peoples is related to acidic compounds such as Palmitic acid, Linoleic acid and Oleic acid.

Keywords

References

  1. Yousefi M. Flora of Iran. Tehran: Payam-e-Noor University Press. 2009.
  2. Ricki Maryshany A, Ebrahimi M, Shirmohammadi E. Allelopathy effects of Trifolium alexandrium on germination and nutrient uptake in medicinal plant Peganum harmala L. Journal of Medicinal Plants and By-products. 2017;1:71-79.
  3. Zargari A. Medicinal plants. University of Tehran press. 1992.
  4. Boskabadi H, Maamouri G, Mafinejad S. The effect of traditional remedies (Camel's Thorn, Flixweed and Sugar Water) on idiopathic neonatal jaundice. Iranian Journal of Pediatrics. 2011;21:325-330.
  5. Delnavaz Hashemlouian B, Atai Azimi A. Medicinal and edible properties of plants. Islamic Azad University, Saveh Branch Press. 2007.
  6. Ahvazi M, Mozaffarian V, Nejadsatari T, Mojab F, Charkhchiyan MM, Khalighi-Sigaroodi F, Ajani Y. Medicinal application of native plants (Lamiaceae and Rosaceae family) in Alamut region in Gazvin province. Med. Plants. 2007;6:74-84.
  7. Sharififar F, Moharramkhani M. R, Fragrant F, Babakhanlu P, Khodami M. Ethnobotanical study of medicinal plants in Jopar region of Kerman province. J Kerman University of Medical Sciences. 2013;1:37-51.
  8. Haji Ali Mohammadi H, Taghavi Shirazi M, Ghorbani A. Atlas of Iranian herbs. Quarterly Journal of Social Sciences. 2006;34-35:175-198.
  9. Silva N, Fernandes Júnior A. Biological properties of medicinal plants: a review of their antimicrobial activity. J. Venom. Anim. Toxins incl. Trop. Dis. 2010;16:402-413.
  10. Mirshekar M. Ebrahimi M. Ajoorlo M. Ethnobotanical study and traditional uses of some medicinal plants in Khash city. J Islamic and Iranian Traditional Med. 2019;9:361-371.
  11. Feng CG, Zhang LX, Liu X. Progress in research of aldose reductase inhibitor in traditional medicinal herbs. Zhongguo Zhong Yao Za Zhi. 2005;30:1496-1500 (In Chinensis).
  12. Huang ST, Chen AP. Traditional Chinese medicine and infertility. Curr Opin Obstet Gynecol. 2008;20:211-215.
  13. Ebrahimi M, Ranjbar S. Essential oils of Salvia hydrangea ex Benth. from Kiasar-Hezarjarib regions, Iran-impact of environmental factors as quality determinants. Journal of Medicinal Plants and By-products. 2016;2:159-167.
  14. Najafi F, Kouchaki AR, Rezvani Moghadam P, Rastgoo M. Study of folk medicine of Poone Sai Binaloodi (Nepeta binaludensis), a rare and endangered species from Iran, Quarterly Journal of Medicinal Plants. 2009;30:31-30.
  15. Mosaddegh M, Naghibia F, Moazzenia H, Pirania A, Esmaeilia S. Ethnobotanical survey of herbal remedies traditionally used in Kohghiluyeh va Boyer Ahmad province of Iran. Ethnopharmacol. 2012;141;80-95.
  16. Panwar J, Tarafdar JC. Distribution of three endangered medicinal plant species and their colonization with arbuscular mycorrhizal fungi. J. Arid Environ. 2006;5:337-350.
  17. Negi MS, Singh A, Lakshmikumaran M. Genetic variation and relationship among and within Withania species as revealed by AFLP markers. Genome. 2000;43:975-980.
  18. Valizadeh J, Valizadeh M. Development of efficient micro propagation protocol for Withania coagulans (Stocks) Dunal. Afr. J. Biotechnol. 2011;10:7611-7616.
  19. Salehi Surmaghi MH. Medicinal plants and phytotherapy. Donyay Taghziah Press, Tehran. 2010.
  20. Abouzid SF, El-Bassuony AA, Nasib A, Khan S, Qureshi J, Choudhary MI. Withaferin A production by root cultures of Withania coagulans. Int. J. Appl. Res. Nat. Prod. 2010;3:23-27.
  21. Khosravi H, Ebrahimi M, Rigi M. Effects of rangeland exclusion on plant cover and soil properties in a steppe rangeland of Southeastern Iran Hamideh. Arid. Land Res. Manag. 2017. DOI: 10.1080/15324982.2017.1310147
  22. Heydaria M, Heydarib H, Saadatic A, Gharehbegloud M, Tafarojie J, Akbarif A. Ethnomedicine for neonatal jaundice: A cross-sectional survey in Qom, Iran Ethnopharmacol. 2016;193:637-642
  23. Khajoei Nasab F, Khosravi AR, Ethnobotanical study of medicinal plants of Sirjan in Kerman Province, Iran. Ethnopharmacol. 2014;154;190-197.
  24. Moradi L, Dolatkhahi M, Darabi H, Nabipour A. Ethnopharmacology of medicinal plants of Genaveh port, Iran South Med J. 2014;5:959-973.
  25. Cochran WG. Sampling techniques. John Wiley and Sons, New York. 1977.
  26. Adams RP. Identification of essential oil components by gas chromatography/mass spectrometry, Allured Press, Carol Stream, IL. USA. 1995.
  27. Dolatkhahi M, Ghorbani Nohooji M, Dolatkhahi M, Mehrafarin A, Amini Nejad G. Ethnobotanical study of medicinal plants in Kazeroon, Iran: identification, distribution and traditional usage. J Medicinal Plants. 2012;42:163-178.
  28. Ziai SA, Mesgarpour B, Shabestari A. Medicinal plants: evidence-based contraindications and drug interactions.Teymourzadeh Publications, Tehran. 2005.
  29. Sajjadi SE, Batooli H, Ghanbari A. Collection, evaluation and ethnobotany of Kashan medicinal plants. Journal of Islamic and Iranian Traditional Medicine. 2011;2:29-36.
  30. Bakhtawar SH, Mughal T, Naeem I. Chemical composition of the essential oil of Withania coagulans. Asian J. Chem. 2010;1:122-126.
  31. Ali A, Jameel M, Ali M. Analysis of fatty acid composition of Withania coagulans fruits by gas chromatography/mass spectrometry. Research Journal of Pharmacognosy. 2017;4:1-6.
  32. Mishra J, Dash AK, Mishra SHN, Gupta AK. Withania Coagulans in Treatment of diabetics and some other diseases: a review. Res J Pharm Biol Chem Sci. 2013;4:1251-1258.
  33. Bare N, Jadhav P. Pharmaceutical importance of Withania Coagulans in health and diseases. Int J Adv Sci Eng Inf Technol. 2017;5:41-44.
  34. Maurya R, Akanksha, Jayendra. Chemistry and pharmacology of Withania coagulans: an Ayurvedic remedy. J Pharm Pharmacol. 2010;62:153-60.
  35. Jaiswal D, Rai PK, Watal G. Antidiabetic effect of Withania coagulans in experimental rats. Clin Chem. 2009;24:88-93.
  36. Nagareddy PR, Lakshmana M. Withania somnifera improves bone calcification in calcium-deficient ovariectomized rats. J. Pharm. Pharmacol. 2006;58:513-519.
  37. Prasad SK, Kumar R, Patel DK, Hemalatha S. Wound healing activity of Withania coagulans in streptozotocin-induced diabetic rats. Pharm Biol. 2010;48:1397-1404.
  38. Khodaei M, Jafari M, Noori M. Remedial use of withanolides from Withania coagolans (Stocks) dunal. Int. J. Adv. Life Sci. 2012;2:6-19.
  39. Gupta V, Keshari BB. Withania coagulans (Paneer doda): a review. Int. j. Ayurvedic herb. med. 2013;3:13330-1336.
Journal of Medicinal plants and By-Products
Volume 11, Issue 2
September 2022
Pages 277-285

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