Detection of some Active Phenolic Compounds in Two Local Microalgae Species Chlorella Sorokiniana Shihira & R.W.Krauss and Coelastrella Saipanensis N.Hanagata
The present study aimed to characterise some active phenolic compounds in the alcoholic extract of two types of local microalgae, Chlorella sorokiniana Shihira & R.W.Kraussand Coelastrella saipanensis N.Hanagata These compounds were detected using HPLC device. The results showed that there were four types of active phenolic compounds, which were Gallic acid, Catechine, Ferulic acid and Hydrobenzoic acid. The highest concentration of all these compounds found in Coelastrella saipanensis. Concerning the compounds, the highest value was for Gallic acid and it was 45. 85 ppm, while the lowest value was for Hydrobenzoic acid and it was 14. 28 ppm in Chlorella sorokiniana. It is that these compounds have vital activity in inhibiting different types of pathogenic bacteria and fungi as shown in many previous studies. From this study, we conclude the ability to produce these active compounds from both algae under natural conditions of growth.
Chu Y., Li, S., Xie P., Chen X., Li X., Ho S.H. New insight into the concentration-dependent removal of multiple antibiotics by Chlorella sorokiniana. Bioresource Technol. 2023; 385: 129409.
Abubakar A.L., Lawal A. Carotenoids and Nutraceuticals Production from Green Microalgae (Dunaliella and Chlorella). Nigerian Journal of Basic and Applied Sciences. 2023; 31(2): 91-96.
Sikiru A., Arangasamy A., Alemede I., Egena S., Bhatta R., Rao S. In vitro evaluation of antioxidant properties of Chlorella vulgaris and its derivatives for use as antioxidant supplements in animal production. The Indian J Animal Sci. 2024; 94(1):88-91.
Zakaria S.M., Mustapa Kamal S.M., Harun M.R., Omar R., Siajam S.I. Subcritical water technology for extraction of phenolic compounds from Chlorella sp. microalgae and assessment on its antioxidant activity. Mol. 2017; 22(7): 1105.
Zaytseva A., Chekanov K., Zaytsev P., Bakhareva D., Gorelova O., Kochkin D., Lobakova E. Sunscreen effect exerted by secondary carotenoids and mycosporine-like amino acids in the aeroterrestrial chlorophyte Coelastrella rubescens under high light and UV-A irradiation. Plants. 2021; 10(12): 2601.
Nayana K., Vidya D., Soorya K., Dineshan A., Menon A.S., Mambad R., Arunkumar K. Effect of Volume and Surface Area on Growth and Productivity of Microalgae in Culture System. BioEnergy Res. 2023; 16(2): 1013-1025.
Saranya C., Hemalatha A., Parthiban C., Anantharaman P. Evaluation of antioxidant properties, total phenolic and carotenoid content of Chaetoceros calcitrans, Chlorella salina and Isochrysis galbana. Int. J. Curr. Microbiol. App. Sci. 2014;3(8): 365-377.
Fadeel, Z.G., Hassan, F.M. & Al-Mahdawe, M.M. (2024). The Impact of pH and Growth Phases on Photosynthetic Pigments and Carotene of Coelastrella saipanensis N. Hanagata (Scenedsmacese, Shaerophleales). J. Glob. Innov. Agric. Sci., 2024, 12(3):685-692.
Rahmawati I., Pratama A.W., Pratama S.A., Khozin M.N., Firmanda A., Irawan F. H., Sucipto T.H., et al. Gallic acid: A promising bioactive agent for food preservation and sustainable packaging development. Case Studies in Chemical and Environmental Engineering. 2024;10: 100776.
Xiang Z., Guan H., Zhao X., Xie Q., Xie Z., Cai F., Wang, C., et al. Dietary gallic acid as an antioxidant: A review of its food industry applications, health benefits, bioavailability, nano-delivery systems, and drug interactions. Food Res Int. 2024;114068.
Alshatwi A.A. Catechin hydrate suppresses MCF-7 proliferation through TP53/Caspase-mediated apoptosis. J Experimental Clinical Cancer Res. 2010; 29: 1-9.
Almatroodi S.A., Almatroudi A., Khan A.A., Alhumaydhi F.A., Alsahli M.A., Rahmani A.H. Potential therapeutic targets of epigallocatechin gallate (EGCG), the most abundant catechin in green tea, and its role in the therapy of various types of cancer. Mol. 2020; 25(14): 3146.
Pyrzynska K. Ferulic acid—a brief review of its extraction, bioavailability and biological activity. Separations. 2024; 11(7), 204.
Khatun M.M., Bhuia M.S., Chowdhury R., Sheikh S., Ajmee A., Mollah F., Islam M.T. Potential utilization of ferulic acid and its derivatives in the management of metabolic diseases and disorders: An insight into mechanisms. Cellular Signalling. 2024;121:111291.
Tsagogiannis E., Asimakoula S., Drainas A.P., Marinakos O., Boti V.I., Kosma I.S., Koukkou A.I. Elucidation of 4-Hydroxybenzoic Acid Catabolic Pathways in Pseudarthrobacter phenanthrenivorans Sphe3. Int J Mol Sci. 2024;25(2), 843.
Huo Z.Y., Shi X.C., Wang, Y.X., Jiang Y. H., Zhu G.Y., Herrera-Balandrano D.D., Laborda P. Antifungal and elicitor activities of p-hydroxybenzoic acid for the control of aflatoxigenic Aspergillus flavus in kiwifruit. Food Research International. 2023; 173: 113331.
Fadeel Z.G., Al-Mahdawe M.M., Hassan F.M. Thioflavin T Production in Coelastrella saipanensis LC752948. 1: Impact of Sodium Chloride, growth phases, and their effect on growth parameters. Baghdad Sci J. 2024.
Mittal S. Thin layer chromatography and high pressur liquid chromatography profiling of plant extracts of Viola odorata Linn. of Pharma Int J Bio Sci. 2013; 4(1):B542-B549.
Radovanović B., Mladenović J., Radovanović A., Pavlović R., Nikolić V. Phenolic composition, antioxidant, antimicrobial and cytotoxic activites of Allium porrum L. (Serbia) extracts. J Food Nutr Res. 2015; 3(9):564-9.
Rossi G., Woods F.M., Leisner C.P. Quantification of total phenolic, anthocyanin, and flavonoid content in a diverse panel of blueberry cultivars and ecotypes. HortScience. 2022; 57(8): 901-909.
Marhri A., Rbah Y., Allay A., Boumediene M., Tikent A., Benmoumen A., Addi M. Comparative Analysis of Antioxidant Potency and Phenolic Compounds in Fruit Peel of Opuntia robusta, Opuntia dillenii, and Opuntia ficus-indica Using HPLC‐DAD Profiling. J Food Quality. 2024;(1): 2742606.
Lattanzio V. Phenolic compounds: introduction 50. Nat. Prod. 2013; 1543-1580.
Nayana K., Babu V.S., Vidya D., Sudhakar M.P., Arunkumar K. Growth and productivity of Haematococcus pluvialis and Coelastrella saipanensis by photosystem modulation for understanding the heterotrophic nutritional strategy for bioremediation application. Environ Res. 2024;245: 118077.
Tang D.Y.Y., Khoo K.S., Chew K.W., Tao Y., Ho S.H., Show P.L. Potential utilization of bioproducts from microalgae for the quality enhancement of natural products. Bioresource Technol. 2020; 304: 122997.
Vidya D., Nayana K., Sreelakshmi M., Keerthi K.V., Mohan K.S., Sudhakar M.P., Arunkumar K. A sustainable cultivation of microalgae using dairy and fish wastes for enhanced biomass and bio-product production. Biomass Conversion and Biorefinery. 2021;1-15.
Nayana K., Sudhakar M.P., Arunkumar K. Biorefinery potential of Coelastrella biomass for fuel and bioproducts—a review. Biomass Conversion and Biorefinery. 2022; 1-14.
Toshkova-Yotova, T., Pilarski, P., Yocheva, L., Petrova, D., and Chaneva, G. 2020. Screening of antimicrobial and antioxidant properties of green microalga Coelastrella sp. BGV. Oxidation Communications, 43(2): 265-279.
Fadeel, Z. G. (2025). Detection of some Active Phenolic Compounds in Two Local Microalgae Species Chlorella Sorokiniana Shihira & R.W.Krauss and Coelastrella Saipanensis N.Hanagata. Journal of Medicinal plants and By-products, 14(4), 370-373. doi: 10.22034/jmpb.2024.367499.1797
MLA
Fadeel, Z. G. . "Detection of some Active Phenolic Compounds in Two Local Microalgae Species Chlorella Sorokiniana Shihira & R.W.Krauss and Coelastrella Saipanensis N.Hanagata", Journal of Medicinal plants and By-products, 14, 4, 2025, 370-373. doi: 10.22034/jmpb.2024.367499.1797
HARVARD
Fadeel, Z. G. (2025). 'Detection of some Active Phenolic Compounds in Two Local Microalgae Species Chlorella Sorokiniana Shihira & R.W.Krauss and Coelastrella Saipanensis N.Hanagata', Journal of Medicinal plants and By-products, 14(4), pp. 370-373. doi: 10.22034/jmpb.2024.367499.1797
CHICAGO
Z. G. Fadeel, "Detection of some Active Phenolic Compounds in Two Local Microalgae Species Chlorella Sorokiniana Shihira & R.W.Krauss and Coelastrella Saipanensis N.Hanagata," Journal of Medicinal plants and By-products, 14 4 (2025): 370-373, doi: 10.22034/jmpb.2024.367499.1797
VANCOUVER
Fadeel, Z. G. Detection of some Active Phenolic Compounds in Two Local Microalgae Species Chlorella Sorokiniana Shihira & R.W.Krauss and Coelastrella Saipanensis N.Hanagata. Journal of Medicinal plants and By-products, 2025; 14(4): 370-373. doi: 10.22034/jmpb.2024.367499.1797