Antioxidant Activity and Biovariables Improvement via Pomegranate Flower Methanolic Extract in Albino Rats Dosed by CdSNPs

Al-Obaidi, Fiham Jassim; Jasim, Ridhab Ajeel; AlRawi, Marwa Shakib; Ramizy, Asmiet; Almehemdi, Ali F

doi:10.22034/jmpb.2025.368949.1927

Antioxidant Activity and Biovariables Improvement via Pomegranate Flower Methanolic Extract in Albino Rats Dosed by CdSNPs

Articles in Press

Document Type : Research Paper

Authors

¹ Department of Biology, College of Science, University of Anbar, Iraq

² Department of Biology, College for pure Sciences, University of Anbar, Iraq

³ Department of Pharmacology and Toxicology, College of Pharmacy, University of Anbar, Iraq

⁴ Department of Physics, College of Science, University of Anbar, Iraq

⁵ Department of Conservation Agriculture, Center of Desert Studies, University of Anbar, Iraq

10.22034/jmpb.2025.368949.1927

Abstract

Cadmium (Cd), is a heavy metal that is toxic to both animals as well as humans Pomegranate flowers are an ancient herb used in conventional Chinese medicine. Pomegranate flower extract is advantageous. Pomegranate flowers have been collected from various locations, in the lab, a nano-cadmium sulfide solution was also made, and the nanoparticles (NPs) were viewed under an electronic microscope while their physical characteristics were investigated. The experiment included 5 groups of white rats (1 positive control), (1 negative control), and (3 groups for the treatment trial). The rats were dosed with the toxic substance of cadmium sulfide at regular intervals, then after 30 days the rats were dosed with pomegranate flower methanolic extract. Blood was collected from around the heart of all mice in the experiment, study (ALP, ALT, AST), (urea and creatinine), and (GPX, Catalase, and MDA) as an indicator of the therapeutic role of the alcoholic extract of pomegranate flowers. The present research's findings demonstrated that rats exposed to pomegranate flower methanolic extract improved in all required variables. Our results confirm the therapeutic role of the pomegranate plant and suggest that supplementation may be beneficial and treat many pathological problems, including kidney and liver problems.

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