Comprehensive Study of the Hemostatic Properties of Achillea millefolium and Silver Nanoparticles

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Document Type : Research Paper

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Department of Biotechnology, Faculty of Biological Science, Alzahra University, Tehran, Iran

Abstract

The Achillea millefolium plant is used in traditional medicine for various purposes, such as wound healing, disinfection, etc., due to its bioactive compounds, such as sesquiterpenes and flavonoids. This study aimed to investigate the hemostatic properties of silver nanoparticles, Achillea millefolium extract, as well as the effect of combining these two substances and the antibacterial effect of yarrow. To conduct this study, first, the Achillea millefolium plant was extracted using ethanol, and then GC-MS was used to examine the components of the extract. Also, coagulation properties were evaluated using PT, PTT, and CT tests. In order to investigate the antibacterial properties of Achillea millefolium extract, two species of Staphylococcus aureus and Escherichia coli were used. The results showed that silver nanoparticles and Achillea millefolium extract have hemostatic properties and are able to reduce blood clotting time, and Achillea millefolium also has antibacterial properties against Staphylococcus aureus. Given the hemostatic and antibacterial properties of Achillea millefolium, this plant can be used to stop bleeding from wounds.

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Journal of Medicinal plants and By-products

Articles in Press, Accepted Manuscript
Available Online from 14 December 2025

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